Chromatographic methods for carcinogenic/mutagenic nitropolycyclic aromatic hydrocarbons.

Nitropolycyclic aromatic hydrocarbons (NPAHs), which are known to be carcinogenic and/or mutagenic, are considered to be one of the air pollutants that cause lung cancer. In the last two decades, a number of sensitive and selective methods have been developed for the determination of NPAHs and related compounds in environmental and biological samples. This paper describes the state of the art of the methods and applications.