sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

GF88419695

Nickel, insulated wire, 50m, conductor diameter 0.025mm, insulation thickness 0.0035mm, polyimide insulation

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

GF93039633

Nickel, wire reel, 200m, diameter 0.125mm, annealed, 99.98%

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

GF94031658

Nickel, foil, light tested, 25x25mm, thickness 0.015mm, 99.9%

GF30288539

Nickel, wire reel, 50m, diameter 1.0mm, as drawn, 99%

GF45193697

Nickel, rod, 100mm, diameter 2.0mm, annealed, 99%

GF17660594

Nickel, wire reel, 1m, diameter 2.0mm, hard, 99.98%

GF90754241

Nickel, rod, 100mm, diameter 40mm, 99%

GF81996014

Nickel, pellets, 100g, max. size 10mm, 99.99+%

GF44632818

Nickel, foil, light tested, 100x100mm, thickness 0.015mm, 99.9%

767484

Sigma-Aldrich

Nickel, sputtering target, diam. × thickness 2.00 in. × 0.25 in., 99.95% trace metals basis

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

GF21754100

Nickel, rod, 500mm, diameter 12.7mm, 99.98%

GF32802511

Nickel, foil, 25mm disks, thickness 0.05mm, as rolled, 99.98%

GF51944665

Nickel, rod, 200mm, diameter 3.0mm, 99%

GF09893302

Nickel, tube, 1000mm, outside diameter 2.4mm, inside diameter 2.248mm, wall thickness 0.076mm, hard, 99.5%

GF25814077

Nickel, foil, 15mm disks, thickness 0.125mm, annealed, 99%

GF61221989

Nickel, foil, 4mm disks, thickness 0.5mm, as rolled, 100%

GF01381407

Nickel, tube, 100mm, outside diameter 1.8mm, inside diameter 1.6mm, wall thickness 0.1mm, hard, 99.5%

GF36396973

Nickel, foil, 15mm disks, thickness 0.075mm, as rolled, 99.98%

GF34230800

Nickel, rod, 500mm, diameter 3.0mm, 99%

GF66976116

Nickel, tube, 200mm, outside diameter 0.35mm, inside diameter 0.3mm, wall thickness 0.025mm, hard, 99.5%

GF95115731

Nickel, foil, 50mm disks, thickness 0.0075mm, 99.95%

GF44385903

Nickel, rod, 500mm, diameter 1.5mm, 99.99+%

GF20561385

Nickel, rod, 100mm, diameter 5.0mm, 99.99+%

GF03088627

Nickel, foil, 50mm disks, thickness 0.05mm, as rolled, 99.98%

GF26171344

Nickel, tube, 100mm, outside diameter 1.57mm, inside diameter 0.63mm, wall thickness 0.47mm, hard, 99.5%