Merck

Need for speed: mechanical regulation of a replicative helicase.

Cell (2007-07-03)
Taekjip Ha
ABSTRACT

There is much debate about how helicases unwind DNA during DNA replication and how their activity is regulated. In this issue, Johnson et al. (2007) shed light on this conundrum using a single molecule approach to dissect the behavior of the T7 DNA helicase.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
MISSION® shRNA Human Gene Family Set, Bacterial Glycerol Stock, Helicases
Sigma-Aldrich
MISSION® shRNA Human Gene Family Set, DNA, Helicases
Sigma-Aldrich
MISSION® shRNA Human Gene Family Set, Lentiviral Particles, Helicases