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Merck

ABCA1

ATP-binding cassette, sub-family A (ABC1), member 1

Synonimy:
ABC-1, ABC1, CERP, HDLDT1, TGD
Gatunek:
Human ABCA1 (19), Mouse Abca1 (11303), Rat Abca1 (313210), chicken ABCA1 (373945), cow ABCA1 (535379), sheep ABCA1 (101119015), domestic cat ABCA1 (101083885), Horse ABCA1 (100054241), dog ABCA1 (481651), Thale Cress ABCA1 (818768) ...Więcej
Identyfikator UniProtKB:
O95477, Q5VX33, Q96S56, Q96T85, Q9NQV4, Q9UN06, Q9UN07, Q9UN08
Identyfikator genu:
  • Human(19) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
  • Mouse(11303) ATP-binding cassette, sub-family A (ABC1), member 1
  • Rat(313210) ATP-binding cassette, subfamily A (ABC1), member 1
  • chicken(373945) ATP-binding cassette, sub-family A (ABC1), member 1
  • cow(535379) ATP-binding cassette, sub-family A (ABC1), member 1
  • sheep(101119015) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic cat(101083885) ATP-binding cassette, sub-family A (ABC1), member 1
  • Horse(100054241) ATP-binding cassette, sub-family A (ABC1), member 1
  • dog(481651) ATP-binding cassette, sub-family A (ABC1), member 1
  • Thale Cress(818768) ABC transporter A family member 1
  • naked mole-rat(101704546) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic guinea pig(100720792) ATP-binding cassette, sub-family A (ABC1), member 1
  • Domestic Rabbit(100356765) ATP-binding cassette, sub-family A (ABC1), member 1

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
T2320
T0901317, ≥98%,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB2106639
Anti-ABCA1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot
HPA057283
Anty-ABCA1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
SAB4300712
Anty-ABCA1, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
MAB10005
Anti-ABCA1 Antibody, clone AB.H10, clone AB.H10, Chemicon®, from mouse,
Reaktywność gatunkowa
chicken, human, mouse
Zastosowanie
ELISA
immunohistochemistry
immunoprecipitation (IP)
western blot
MABN893
Anti-ABCA1 Antibody, clone MABI98-7, clone MAB198-7, from rat,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
1563309
Probucol, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
P9672
Probucol, analytical standard,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EMU068891
MISSION® esiRNA, targeting mouse Abca1,
Gatunek
mouse