ABCA4
ATP-binding cassette, sub-family A (ABC1), member 4
Synonimy:
ABC10, ABCR, ARMD2, CORD3, FFM, RMP, RP19, STGD, STGD1
Gatunek:
Human ABCA4 (24), Mouse Abca4 (11304), Rat Abca4 (310836), chicken ABCA4 (424490), Horse ABCA4 (100058746), dog ABCA4 (444852), domestic cat ABCA4 (101099571), Thale Cress ABCA4 (823929), naked mole-rat Abca4 (101725111), domestic guinea pig Abca4 (100725431) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(24) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is a retina-specific ABC transporter with N-retinylidene-PE as a substrate. It is expressed exclusively in retina photoreceptor cells, indicating the gene product mediates transport of an essental molecule across the photoreceptor cell membrane. Mutations in this gene are found in patients diagnosed with Stargardt disease, a form of juvenile-onset macular degeneration. Mutations in this gene are also associated with retinitis pigmentosa-19, cone-rod dystrophy type 3, early-onset severe retinal dystrophy, fundus flavimaculatus, and macular degeneration age-related 2. [provided by RefSeq, Jul 2008]
- Mouse(11304) ATP-binding cassette, sub-family A (ABC1), member 4
- Rat(310836) ATP-binding cassette, subfamily A (ABC1), member 4
- chicken(424490) ATP-binding cassette, sub-family A (ABC1), member 4
- Horse(100058746) ATP-binding cassette, sub-family A (ABC1), member 4
- dog(444852) ATP-binding cassette, sub-family A (ABC1), member 4
- domestic cat(101099571) ATP-binding cassette, sub-family A (ABC1), member 4
- Thale Cress(823929) ATP binding cassette subfamily A4
- naked mole-rat(101725111) ATP-binding cassette, sub-family A (ABC1), member 4
- domestic guinea pig(100725431) ATP-binding cassette, sub-family A (ABC1), member 4
- sheep(101107561) ATP-binding cassette, sub-family A (ABC1), member 4
- cow(281584) ATP-binding cassette, sub-family A (ABC1), member 4
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-ABCA4, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-ABCA4, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Przeciwciało anty-ABCA4, klon 5D7.1, clone 5D7.1, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-ABCA4 Antibody, clone 5B4, clone 5B4, from mouse,
Reaktywność gatunkowa
bovine, human, mouse
Zastosowanie
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anty-ABCA4, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
esiRNA
Numer produktu
Opis
Gatunek