ABCC8
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
Synonimy:
ABC36, HHF1, HI, HRINS, MRP8, PHHI, SUR, SUR1, SUR1delta2, TNDM2
Gatunek:
Human ABCC8 (6833), Mouse Abcc8 (20927), Rat Abcc8 (25559), domestic cat ABCC8 (101096101), sheep ABCC8 (101120522), naked mole-rat Abcc8 (101705546), domestic guinea pig Abcc8 (100722700), Zebrafish abcc8 (553281), chicken ABCC8 (423072), dog ABCC8 (485402) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(6833) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a modulator of ATP-sensitive potassium channels and insulin release. Mutations and deficiencies in this protein have been observed in patients with hyperinsulinemic hypoglycemia of infancy, an autosomal recessive disorder of unregulated and high insulin secretion. Mutations have also been associated with non-insulin-dependent diabetes mellitus type II, an autosomal dominant disease of defective insulin secretion. Alternative splicing of this gene has been observed; however, the transcript variants have not been fully described. [provided by RefSeq, Jul 2008]
- Mouse(20927) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- Rat(25559) ATP-binding cassette, subfamily C (CFTR/MRP), member 8
- domestic cat(101096101) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- sheep(101120522) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- naked mole-rat(101705546) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- domestic guinea pig(100722700) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- Zebrafish(553281) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- chicken(423072) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- dog(485402) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- Horse(100071788) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
- cow(538996) ATP-binding cassette, sub-family C (CFTR/MRP), member 8
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ABCC8 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, human, mouse, pig, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-SUR1 Antibody, clone N289/16, clone N289/16, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Monoklonalny anty-Sur1- Fitc, clone S289-16, purified immunoglobulin,
Reaktywność gatunkowa
hamster, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoklonalny anty-Sur1- Atto 594, clone S289-16, purified immunoglobulin,
Reaktywność gatunkowa
hamster, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-ABCC8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Small Molecule - Blocker
Numer produktu
Opis
Gatunek
Glimepiride for system suitability, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human