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Merck

ABCD1

ATP-binding cassette, sub-family D (ALD), member 1

Synonimy:
ABC42, ALD, ALDP, AMN
Gatunek:
Human ABCD1 (215), Mouse Abcd1 (11666), Rat Abcd1 (363516), sheep ABCD1 (101122673), Domestic Rabbit ABCD1 (100328741), Zebrafish abcd1 (566367), dog ABCD1 (612520), domestic cat ABCD1 (101088223), cow ABCD1 (515178), naked mole-rat Abcd1 (101720585)
Identyfikator UniProtKB:
P33897, Q6GTZ2
Identyfikator genu:
  • Human(215) Summary: The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in this gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system. [provided by RefSeq, Jul 2008]
  • Mouse(11666) ATP-binding cassette, sub-family D (ALD), member 1
  • Rat(363516) ATP-binding cassette, subfamily D (ALD), member 1
  • sheep(101122673) ATP-binding cassette, sub-family D (ALD), member 1
  • Domestic Rabbit(100328741) ATP-binding cassette, sub-family D (ALD), member 1
  • Zebrafish(566367) ATP-binding cassette, sub-family D (ALD), member 1
  • dog(612520) ATP-binding cassette, sub-family D (ALD), member 1
  • domestic cat(101088223) ATP-binding cassette, sub-family D (ALD), member 1
  • cow(515178) ATP-binding cassette, sub-family D (ALD), member 1
  • naked mole-rat(101720585) ATP-binding cassette, sub-family D (ALD), member 1
  • domestic guinea pig(100713152) ATP-binding cassette, sub-family D (ALD), member 1

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB6012494
KD-Validated Anti ABCD1 Antibody, clone 23GB3125, Rabbit Monoclonal, clone 23GB3125, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
SAB4301908
Anti-ABCD1, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
WH0000215M1
Monoclonal Anti-ABCD1 antibody produced in mouse, clone 4B5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
MAB2164
Przeciwciało przeciwko białku adrenoleukodystrofii, n.a. 279-482, klon 2AL-1D6, ascites fluid, clone 2AL-1D6, Chemicon®,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunocytochemistry
immunohistochemistry
western blot
MAB2162
Przeciwciało przeciwko białku adrenoleukodystrofii, n.a. 495-648, klon 1AL-2B4, ascites fluid, clone 1AL-2B4, Chemicon®,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunocytochemistry
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
EHU028221
MISSION® esiRNA, targeting human ABCD1,
Gatunek
human
EMU019811
MISSION® esiRNA, targeting mouse Abcd1,
Gatunek
mouse