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Merck

ABCG2

ATP-binding cassette, sub-family G (WHITE), member 2

Synonimy:
ABC15, ABCP, BCRP, BCRP1, BMDP, CD338, CDw338, EST157481, GOUT1, MRX, MXR, MXR1, UAQTL1
Gatunek:
Human ABCG2 (9429), Mouse Abcg2 (26357), Rat Abcg2 (312382), domestic guinea pig Abcg2 (100723442), domestic cat ABCG2 (101094017), chicken ABCG2 (423767), dog ABCG2 (478472), Horse ABCG2 (100034164), cow ABCG2 (536203), sheep ABCG2 (780508) ...Więcej
Identyfikator UniProtKB:
Q9UNQ0, A0A1W3, A8K1T5, O95374, Q53ZQ1, Q569L4, Q5YLG4, Q86V64
Identyfikator genu:
  • Human(9429) Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, this protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. It likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. Significant expression of this protein has been observed in the placenta, which may suggest a potential role for this molecule in placenta tissue. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(26357) ATP-binding cassette, sub-family G (WHITE), member 2
  • Rat(312382) ATP-binding cassette, subfamily G (WHITE), member 2
  • domestic guinea pig(100723442) ATP-binding cassette, sub-family G (WHITE), member 2
  • domestic cat(101094017) ATP-binding cassette, sub-family G (WHITE), member 2
  • chicken(423767) ATP-binding cassette, sub-family G (WHITE), member 2
  • dog(478472) ATP-binding cassette, sub-family G (WHITE), member 2
  • Horse(100034164) ATP-binding cassette, sub-family G (WHITE), member 2
  • cow(536203) ATP-binding cassette, sub-family G (WHITE), member 2
  • sheep(780508) ATP-binding cassette, sub-family G (WHITE), member 2
  • Domestic Rabbit(100008640) ATP-binding cassette, sub-family G (WHITE), member 2
  • Goat(100860857) ATP-binding cassette, sub-family G (WHITE), member 2

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB5700094
Przeciwciało anty-ABCG2wytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
SAB5701106
Anti-ABCG2, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
MAB4145
Anti-BCRP Antibody, clone BXP-34, culture supernatant, clone BXP-34, Chemicon®,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
immunohistochemistry
ZRB1217
Anti-BCRP (ABCG2) Antibody, clone 10K5 , ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
immunohistochemistry
western blot
B7185
Anti-Breast Cancer Resistance Protein antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot

Cell Lines

Numer produktu
Opis
Gatunek
MTOX1021
HepaRG™ Komórki BCRP (-/-), one vial,
Gatunek
human
MTOX1302
Psi nokaut MDR1, ludzki podwójny nokaut BCRP/OATP2B1 w komórkach MDCKII, ,
Gatunek
human
MTOX1304
Canine MDR1 Knockout, Human BCRP Knockin MDCKII Cells, ,
Gatunek
human
MTOX1006
Komórki Caco-2 z podwójnym nokautem BCRP/MRP2, one vial,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EMU090051
MISSION® esiRNA, targeting mouse Abcg2,
Gatunek
mouse
EHU012921
MISSION® esiRNA, targeting human ABCG2,
Gatunek
human