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Merck

ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4

Synonimy:
ADAMTS-2, ADAMTS-4, ADMP-1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(9507) Summary: This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma. [provided by RefSeq, Jul 2008]
  • Mouse(240913) a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
  • Rat(66015) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • domestic cat(101089488) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • Horse(100033914) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • dog(488651) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • sheep(101106565) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • cow(286806) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • naked mole-rat(101702362) ADAM metallopeptidase with thrombospondin type 1 motif, 4
  • domestic guinea pig(100712995) ADAM metallopeptidase with thrombospondin type 1 motif, 4

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human ADAMTS4 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ADAMTS4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anty-ADAMTS4, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anty-ADAMTS4, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-ADAMTS4, affinity isolated antibody,
Reaktywność gatunkowa
bovine, guinea pig, horse, human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ADAMTS4,
Gatunek
human
MISSION® esiRNA, targeting mouse Adamts4,
Gatunek
mouse