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ADRA2C

adrenoceptor alpha 2C

Synonimy:
ADRA2L2, ADRA2RL2, ADRARL2, ALPHA2CAR
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(152) Summary: Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
  • Mouse(11553) adrenergic receptor, alpha 2c
  • Rat(24175) adrenoceptor alpha 2C
  • domestic guinea pig(100135477) adrenergic receptor, alpha 2c
  • domestic guinea pig(101787589) adrenoceptor alpha 2C
  • cow(101902575) adrenoceptor alpha 2C
  • cow(407139) alpha-2C adrenergic receptor
  • sheep(100170319) adrenoceptor alpha 2C
  • Zebrafish(266752) adrenergic, alpha-2C-, receptor
  • chicken(428799) adrenergic, alpha-2C-, receptor
  • dog(488793) adrenoceptor alpha 2C
  • domestic cat(101087990) adrenoceptor alpha 2C
  • domestic cat(100529244) adrenoceptor alpha 2C

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Clonidine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Clonidine hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Clonidine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Xylazine hydrochloride, ≥99.0% (HPLC),
Gatunek
human
Clonidine hydrochloride, solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Idazoxan hydrochloride, ,
Gatunek
human
Yohimbine hydrochloride, ≥98% (HPLC), powder,
Gatunek
human
RX 821002 hydrochloride, solid, ≥98% (HPLC),
Gatunek
human
UK 14,304, ,
Gatunek
human
Mirtazapine for system suitability, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Adrenergic Receptor α-2C antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
Monoklonalna anty-alfa2C receptor adrenergiczny - Atto 390, clone S330A-80, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
western blot
Monoklonalna anty-alfa2C receptor adrenergiczny - Atto 488, clone S330A-80, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
western blot
Monoklonalny anty-alfa-2C, clone S330A-80, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
western blot
Monoklonalny anty-alfa2C receptor adrenergiczny - Apc, clone S330A-80, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Mianserin hydrochloride, ,
Gatunek
human
Agmatine sulfate salt, ≥97%, powder,
Gatunek
human

Small Molecule - Mixed Agonist/Antagonist

Numer produktu
Opis
Gatunek
UK 14,304, ,
Gatunek
human
(−)-Norepinephrine, ≥98%, crystalline,
Gatunek
human, rat
Haloperidol, powder,
Gatunek
human, rat
Clozapine, ,
Gatunek
human, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Adra2c,
Gatunek
mouse