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Merck

AIRE

autoimmune regulator

Synonimy:
AIRE1, APECED, APS1, APSI, PGA1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(326) Summary: This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]
  • Mouse(11634) autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal dystrophy)
  • Rat(294328) autoimmune regulator
  • domestic guinea pig(100729880) autoimmune regulator
  • sheep(101102698) autoimmune regulator
  • cow(784775) autoimmune regulator
  • Zebrafish(100007662) autoimmune regulator
  • chicken(429666) autoimmune regulator
  • dog(487796) autoimmune regulator
  • naked mole-rat(101725873) autoimmune regulator
  • domestic cat(101091039) autoimmune regulator

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-ARE, klon Mab155, clone Mab155, 1 mg/mL, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunocytochemistry

western blot
Anti-AIRE (Isoforms 1 and 2) (AB2) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human AIRE,
Gatunek
human
MISSION® esiRNA, targeting mouse Aire,
Gatunek
mouse