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Merck

APOE

apolipoprotein E

Synonimy:
AD2, LDLCQ5, LPG
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(348) Summary: Chylomicron remnants and very low density lipoprotein (VLDL) remnants are rapidly removed from the circulation by receptor-mediated endocytosis in the liver. Apolipoprotein E, a main apoprotein of the chylomicron, binds to a specific receptor on liver cells and peripheral cells. ApoE is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The APOE gene is mapped to chromosome 19 in a cluster with APOC1 and APOC2. Defects in apolipoprotein E result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. [provided by RefSeq, Jul 2008]
  • Mouse(11816) apolipoprotein E
  • Rat(25728) apolipoprotein E
  • naked mole-rat(101717206) apolipoprotein E
  • domestic guinea pig(100731633) apolipoprotein E
  • cow(281004) apolipoprotein E
  • Domestic Rabbit(100009337) apolipoprotein E
  • dog(476438) apolipoprotein E
  • domestic cat(101086769) apolipoprotein E

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human APOE / Apolipoprotein E ELISA Kit, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ApoE Antibody, clone 3N14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, monkey
Zastosowanie
affinity binding assay
flow cytometry

immunocytochemistry
Anty-Apolipoproteina E mysie mAb (E6D7), liquid, clone E6D7, Calbiochem®,
Reaktywność gatunkowa
human
Zastosowanie
Anti-APOE antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-APOE (N-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat, zebrafish
Zastosowanie
immunohistochemistry
western blot
Anti-ApoE4 Fragment nApoECF Antibody (Asp172), from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
bovine, human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot

Proteins

Numer produktu
Opis
Gatunek
ApoE2 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE), ≥90% (HPLC),
Gatunek
human
Apolipoprotein E4 human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE and HPLC), lyophilized powder,
Gatunek
human
Lipoprotein, high density from human plasma, ≥95% (SDS-PAGE), solution,
Gatunek
human
Lipoprotein, low density from human plasma, ≥95% (SDS-PAGE), solution,
Gatunek
human
Lipoprotein Deficient Serum from human plasma, sterile-filtered, frozen liquid,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Apoe,
Gatunek
mouse