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Merck

APP

amyloid beta (A4) precursor protein

Synonimy:
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2
Gatunek:
Human APP (351), Mouse App (11820), Rat App (54226), fruit fly app (39399), chicken APP (374198), dog APP (403407), domestic cat APP (101085564), cow APP (280722), sheep APP (101111593), domestic guinea pig App (100715302)
Identyfikator UniProtKB:
P05067, B2R5V1, B4DII8, D3DSD1, D3DSD2, D3DSD3, P09000, P78438
Identyfikator genu:
  • Human(351) Summary: This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(11820) amyloid beta (A4) precursor protein
  • Rat(54226) amyloid beta (A4) precursor protein
  • fruit fly(39399) approximated
  • chicken(374198) amyloid beta (A4) precursor protein
  • dog(403407) amyloid beta (A4) precursor protein
  • domestic cat(101085564) amyloid beta (A4) precursor protein
  • cow(280722) amyloid beta (A4) precursor protein
  • sheep(101111593) amyloid beta (A4) precursor protein
  • domestic guinea pig(100715302) amyloid beta (A4) precursor protein
  • naked mole-rat(101724743) amyloid beta (A4) precursor protein

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ELISA

Numer produktu
Opis
Gatunek
EZBRAIN-SET
Test ELISA na ludzki amyloid β40 i amyloid β42 w mózgu, ,
Gatunek
human
RAB0530
Human APP / Amyloid Beta A4 Protein ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Gatunek
human
EZHS42
High Sensitivity Human Amyloid β42 ELISA, This High Sensitivity Human Amyloid β42 ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
Gatunek
human
EZHS40
High Sensitivity Human Amyloid β40 ELISA, This High Sensitivity Human Amyloid β40 ELISA is used to measure & quantify Amyloid β40 levels in Neuroscience research.,
Gatunek
human
EZBRAIN42
Human Amyloid β42 Brain ELISA, This Human Amyloid β42 Brain ELISA is used to measure & quantify Amyloid β42 levels in Neuroscience research.,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
B9934
BTA-1, ≥98% (HPLC), solid,
Gatunek
human
C1386
Curcumin, from Curcuma longa (Turmeric), powder,
Gatunek
human
C7727
Curcumin, ≥94% (curcuminoid content), ≥80% (Curcumin),
Gatunek
human
F8514
Flurbiprofen, cyclooxygenase inhibitor,
Gatunek
human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
A8326
Anti-β-Amyloid Protein (1-40) antibody produced in rabbit, whole antiserum,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
A8354
Anti-β-Amyloid antibody, Mouse monoclonal, clone NAB 228, purified from hybridoma cell culture,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
MABN687
Przeciwciało anty-β-amyloidowe specyficzne dla fibryli, klon B10, przeciwciało AP, clone B10, from camel, alkaline phosphatase conjugate,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
dot blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
ZMS1012
Anti-APP A4 Antibody, clone 22C11 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
canine, human, monkey, mouse, porcine, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
western blot
ABN240
Anti-Amyloid, β 1-40, aβ Antibody, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
bovine, human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot

Proteins

Numer produktu
Opis
Gatunek
A4848
Amyloid β-Protein Fragment 17-40, ≥87% (HPLC), lyophilized powder,
Gatunek
human
A1972
[Asn670, Leu671]-Amyloid β/A4 Precursor Protein 770 Fragment 667-676 trifluoroacetate salt, ≥95% (HPLC), solid,
Gatunek
human
A6933
Acetyl-Amyloid β-Protein Fragment 15-20 Amide, ≥97% (HPLC), powder,
Gatunek
human
A0189
Amyloid β Protein Fragment 1-38, ≥95% (HPLC), powder,
Gatunek
human
A2201
Amyloid β-Protein Fragment 35-25, ≥95% (HPLC),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EMU012021
MISSION® esiRNA, targeting mouse App,
Gatunek
mouse
EHU085701
MISSION® esiRNA, targeting human APP,
Gatunek
human