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BAD

BCL2-associated agonist of cell death

Synonimy:
BBC2, BCL2L8
Gatunek:
Human BAD (572), Mouse Bad (12015), Rat Bad (64639), dog BAD (483763), domestic cat BAD (768269), sheep BAD (780444), cow BAD (615013), naked mole-rat Bad (101726042), domestic guinea pig Bad (100734151)
Identyfikator UniProtKB:
Q92934, O14803, Q6FH21
Identyfikator genu:
  • Human(572) Summary: The protein encoded by this gene is a member of the BCL-2 family. BCL-2 family members are known to be regulators of programmed cell death. This protein positively regulates cell apoptosis by forming heterodimers with BCL-xL and BCL-2, and reversing their death repressor activity. Proapoptotic activity of this protein is regulated through its phosphorylation. Protein kinases AKT and MAP kinase, as well as protein phosphatase calcineurin were found to be involved in the regulation of this protein. Alternative splicing of this gene results in two transcript variants which encode the same isoform. [provided by RefSeq, Jul 2008]
  • Mouse(12015) BCL2-associated agonist of cell death
  • Rat(64639) BCL2-associated agonist of cell death
  • dog(483763) BCL2-associated agonist of cell death
  • domestic cat(768269) BCL2-associated agonist of cell death
  • sheep(780444) BCL2-associated agonist of cell death
  • cow(615013) BCL2-associated agonist of cell death
  • naked mole-rat(101726042) BCL2-associated agonist of cell death
  • domestic guinea pig(100734151) BCL2-associated agonist of cell death

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Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
196487
4-Biphenylacetic acid, 98%,
Gatunek
human
37760
2,3-Dihydroxynaphthalene, ≥98.0% (HPLC),
Gatunek
human
B34729
Biphenyl-4-carboxylic acid, 95%,
Gatunek
human
G8761
(±)-Gossypol from cotton seeds, ≥95% (HPLC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4504114
Anti-phospho-BAD (pSer134) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4504113
Anti-phospho-BAD (pSer91/128) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
SAB4500297
Anti-BAD (Cleaved-Asp71) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
SAB3500336
Anti-BAD antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
WH0000572M2
Monoclonal Anti-BAD antibody produced in mouse, clone 3H8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay
western blot

Proteins

Numer produktu
Opis
Gatunek
SRP5164
BAD, GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU077271
MISSION® esiRNA, targeting human BAD,
Gatunek
human