BCAR3
breast cancer anti-estrogen resistance 3
Synonimy:
NSP2, SH2D3B
Gatunek:
Human BCAR3 (8412), Mouse Bcar3 (29815), Rat Bcar3 (310838), Zebrafish bcar3 (570610), chicken BCAR3 (424494), Domestic Rabbit BCAR3 (100352424), cow BCAR3 (506231), sheep BCAR3 (101106808), domestic cat BCAR3 (101099315), domestic guinea pig Bcar3 (100717989) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(8412) Summary: Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
- Mouse(29815) breast cancer anti-estrogen resistance 3
- Rat(310838) breast cancer anti-estrogen resistance 3
- Zebrafish(570610) breast cancer anti-estrogen resistance 3
- chicken(424494) breast cancer anti-estrogen resistance 3
- Domestic Rabbit(100352424) breast cancer anti-estrogen resistance 3
- cow(506231) breast cancer anti-estrogen resistance 3
- sheep(101106808) breast cancer anti-estrogen resistance 3
- domestic cat(101099315) breast cancer anti-estrogen resistance 3
- domestic guinea pig(100717989) breast cancer anti-estrogen resistance 3
- Horse(100059015) breast cancer anti-estrogen resistance 3
- naked mole-rat(101704053) breast cancer anti-estrogen resistance 3
- dog(479941) breast cancer anti-estrogen resistance 3
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-BCAR3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Rabbit anti-BCAR3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Reaktywność gatunkowa
human
Zastosowanie
immunoprecipitation (IP)
western blot
western blot
Przeciwciało anty-BAR3, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anti-BCAR3 (C-terminal) antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
canine, human, pig
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-BAR3, klon 9D9.1, clone 9D9.1, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
western blot