BCL2L11
BCL2-like 11 (apoptosis facilitator)
Synonimy:
BAM, BIM, BOD
Gatunek:
Human BCL2L11 (10018), Mouse Bcl2l11 (12125), Rat Bcl2l11 (64547), naked mole-rat Bcl2l11 (101721800), domestic guinea pig Bcl2l11 (100725284), domestic cat BCL2L11 (101084615), cow BCL2L11 (507390), domestic cat BCL2L11 (768267), Zebrafish bcl2l11 (100190951), sheep BCL2L11 (100505402)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(10018) Summary: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family and to act as an apoptotic activator. The expression of this gene can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role of this gene in neuronal and lymphocyte apoptosis. Transgenic studies of the mouse counterpart suggested that this gene functions as an essential initiator of apoptosis in thymocyte-negative selection. Several alternatively spliced transcript variants of this gene have been identified. [provided by RefSeq, Jun 2013]
- Mouse(12125) BCL2-like 11 (apoptosis facilitator)
- Rat(64547) BCL2-like 11 (apoptosis facilitator)
- naked mole-rat(101721800) BCL2-like 11 (apoptosis facilitator)
- domestic guinea pig(100725284) BCL2-like 11 (apoptosis facilitator)
- domestic cat(101084615) BCL2-like 11 (apoptosis facilitator)
- cow(507390) BCL2-like 11 (apoptosis facilitator)
- domestic cat(768267) BCL2-like 11 (apoptosis facilitator)
- Zebrafish(100190951) BCL2-like 11
- sheep(100505402) BCL2-like 11 (apoptosis facilitator)
- dog(612867) BCL2-like 11 (apoptosis facilitator)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-BIMprodukowane u królików, ,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało anty-BimEL (pS69) człowiek / (pS65) szczur, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-BIM Antibody, clone 2O18, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
ANTI-BIM BH3 DOMAIN antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot