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BMPR2

bone morphogenetic protein receptor, type II (serine/threonine kinase)

Synonimy:
BMPR-II, BMPR3, BMR2, BRK-3, PPH1, T-ALK
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(659) Summary: This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq, Jul 2008]
  • Mouse(12168) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Rat(140590) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • cow(407127) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • naked mole-rat(101701138) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • Domestic Rabbit(100350246) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(101103793) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic guinea pig(100736232) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • chicken(374147) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • sheep(100294556) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • domestic cat(101096338) bone morphogenetic protein receptor, type II (serine/threonine kinase)
  • dog(478875) bone morphogenetic protein receptor, type II (serine/threonine kinase)

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human BMPR-II ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-BMPR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-BMPR2 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Monoclonal Anti-BMPR2 antibody produced in mouse, clone 3F6, ascites fluid,
Reaktywność gatunkowa
human, monkey, mouse, rat
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anty-BMPR2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Przeciwciało anty-BMPR-II, klon 9F4.1, clone 9F4.1, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Proteins

Numer produktu
Opis
Gatunek
BMPR2 (174-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human BMPR2,
Gatunek
human
MISSION® esiRNA, targeting mouse Bmpr2,
Gatunek
mouse