BUB1
BUB1 mitotic checkpoint serine/threonine kinase
Synonimy:
BUB1A, BUB1L, hBUB1
Gatunek:
Human BUB1 (699), Mouse Bub1 (12235), Rat Bub1 (296137), Zebrafish bub1 (100307076), Domestic Rabbit BUB1 (100352234), sheep BUB1 (101117404), cow BUB1 (514777), Horse BUB1 (100064049), domestic cat BUB1 (101085035), dog BUB1 (100682599) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(699) Summary: This gene encodes a serine/threonine-protein kinase that play a central role in mitosis. The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint. This protein also plays a role in inhibiting the activation of the anaphase promoting complex/cyclosome. This protein may also function in the DNA damage response. Mutations in this gene have been associated with aneuploidy and several forms of cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
- Mouse(12235) budding uninhibited by benzimidazoles 1 homolog (S. cerevisiae)
- Rat(296137) BUB1 mitotic checkpoint serine/threonine kinase
- Zebrafish(100307076) BUB1 mitotic checkpoint serine/threonine kinase
- Domestic Rabbit(100352234) budding uninhibited by benzimidazoles 1 homolog (yeast)
- sheep(101117404) budding uninhibited by benzimidazoles 1 homolog (yeast)
- cow(514777) budding uninhibited by benzimidazoles 1 homolog (yeast)
- Horse(100064049) budding uninhibited by benzimidazoles 1 homolog (yeast)
- domestic cat(101085035) budding uninhibited by benzimidazoles 1 homolog (yeast)
- dog(100682599) budding uninhibited by benzimidazoles 1 homolog (yeast)
- chicken(421226) budding uninhibited by benzimidazoles 1 homolog (yeast)
- domestic guinea pig(100725012) BUB1 mitotic checkpoint serine/threonine kinase
- naked mole-rat(101724275) BUB1 mitotic checkpoint serine/threonine kinase
- fruit fly(33758) Bub1 homologue
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Bub1 Antibody, clone 14H5, clone 14H5, Chemicon®, from mouse,
Reaktywność gatunkowa
human, primate
Zastosowanie
immunocytochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
esiRNA
Numer produktu
Opis
Gatunek