CAPN10
calpain 10
Synonimy:
CANP10, NIDDM1
Gatunek:
Human CAPN10 (11132), Mouse Capn10 (23830), Rat Capn10 (63834), Zebrafish capn10 (570311), domestic guinea pig Capn10 (100725945), dog CAPN10 (607311), naked mole-rat Capn10 (101703723), domestic cat CAPN10 (101089955), chicken CAPN10 (424945), sheep CAPN10 (101104198)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(11132) Summary: Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq, Sep 2010]
- Mouse(23830) calpain 10
- Rat(63834) calpain 10
- Zebrafish(570311) calpain 10
- domestic guinea pig(100725945) calpain 10
- dog(607311) calpain 10
- naked mole-rat(101703723) calpain 10
- domestic cat(101089955) calpain 10
- chicken(424945) calpain 10
- sheep(101104198) calpain 10
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CAPN10 antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-CAPN10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence