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CASP10

caspase 10, apoptosis-related cysteine peptidase

Synonimy:
ALPS2, FLICE2, MCH4
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(843) Summary: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011]
  • cow(100848685) caspase 10, apoptosis-related cysteine peptidase
  • chicken(424081) caspase 10, apoptosis-related cysteine peptidase
  • domestic cat(101085995) caspase 10, apoptosis-related cysteine peptidase
  • naked mole-rat(101712620) caspase 10, apoptosis-related cysteine peptidase
  • domestic guinea pig(100717714) caspase 10, apoptosis-related cysteine peptidase
  • Horse(100068201) caspase 10, apoptosis-related cysteine peptidase
  • dog(488472) caspase 10, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CASP10 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti Caspase 10 Antibody, clone 23GB3330, Rabbit Monoclonal, clone 23GB3330, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunofluorescence

western blot
Przeciwciało anty-Kaspaza-10, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Monoclonal Anti-CASP10 antibody produced in mouse, clone 1D8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
proximity ligation assay
Anti-CASP10 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Caspase Inhibitor, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CASP10,
Gatunek
human