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Merck

CASP2

caspase 2, apoptosis-related cysteine peptidase

Synonimy:
CASP-2, ICH1, NEDD-2, NEDD2, PPP1R57
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(835) Summary: This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
  • Mouse(12366) caspase 2
  • Rat(64314) caspase 2
  • dog(482737) caspase 2, apoptosis-related cysteine peptidase
  • Zebrafish(373118) caspase 2, apoptosis-related cysteine protease
  • chicken(395857) caspase 2, apoptosis-related cysteine peptidase
  • naked mole-rat(101712106) caspase 2, apoptosis-related cysteine peptidase
  • domestic guinea pig(100735399) caspase 2, apoptosis-related cysteine peptidase
  • cow(531419) caspase 2, apoptosis-related cysteine peptidase
  • sheep(101115025) caspase 2, apoptosis-related cysteine peptidase
  • domestic cat(101088318) caspase 2, apoptosis-related cysteine peptidase

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-CASP2 antibody produced in mouse, clone 1C11, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot
Przeciwciało anty-Caspase-2, klon 2Z10F1, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-Caspase 2 Antibody, clone 11B4, clone 11B4, Chemicon®, from rat,
Reaktywność gatunkowa
canine, human, monkey, mouse
Zastosowanie
ELISA
flow cytometry

immunoprecipitation (IP)

western blot
Anti-Caspase 2 Antibody, clone 10C6, clone 10C6, Chemicon®, from rat,
Reaktywność gatunkowa
canine, human, monkey, mouse
Zastosowanie
ELISA
flow cytometry

immunoprecipitation (IP)

western blot
Anti-Caspase-2 Antibody, clone 1H14 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Z-Val-Asp(O-Me)-Val-Ala-Asp(O-Me) fluoromethyl ketone, powder, ≥95%,
Gatunek
mouse, rat, human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CASP2,
Gatunek
human
MISSION® esiRNA, targeting mouse Casp2,
Gatunek
mouse