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Merck

CDC27

cell division cycle 27

Synonimy:
ANAPC3, APC3, CDC27Hs, D0S1430E, D17S978E, HNUC, NUC2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(996) Summary: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae protein Cdc27, and the gene product of Schizosaccharomyces pombe nuc 2. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eucaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction. This protein was shown to interact with mitotic checkpoint proteins including Mad2, p55CDC and BUBR1, and thus may be involved in controlling the timing of mitosis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(217232) cell division cycle 27
  • Rat(360643) cell division cycle 27
  • naked mole-rat(101717421) cell division cycle 27
  • domestic cat(101091234) cell division cycle 27 homolog (S. cerevisiae)
  • fruit fly(38798) CG8610 gene product from transcript CG8610-RB
  • dog(490924) cell division cycle 27 homolog (S. cerevisiae)
  • chicken(419960) cell division cycle 27 homolog (S. cerevisiae)
  • cow(540660) cell division cycle 27 homolog (S. cerevisiae)
  • domestic guinea pig(100731091) cell division cycle 27
  • Zebrafish(30450) cell division cycle 27
  • Horse(100054552) cell division cycle 27 homolog (S. cerevisiae)
  • sheep(101121276) cell division cycle 27 homolog (S. cerevisiae)

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-CCDC27, klon 7U5A3, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-CDC27 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anty-CDC27, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-Cdc27 antibody,Mouse monoclonal, clone AF3.1, purified from hybridoma cell culture,
Reaktywność gatunkowa
xenopus, bovine, canine, human, mouse, rat
Zastosowanie
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

microarray

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CDC27,
Gatunek
human
MISSION® esiRNA, targeting mouse Cdc27,
Gatunek
mouse