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CDH1

cadherin 1, type 1, E-cadherin (epithelial)

Synonimy:
Arc-1, CD324, CDHE, ECAD, LCAM, UVO
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(999) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq, Jul 2008]
  • Mouse(12550) cadherin 1
  • Rat(83502) cadherin 1
  • dog(442858) cadherin 1, type 1, E-cadherin (epithelial)
  • chicken(415860) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(100294601) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic guinea pig(100726210) cadherin 1, type 1, E-cadherin (epithelial)
  • domestic cat(101095391) cadherin 1, type 1, E-cadherin (epithelial)
  • sheep(101119747) cadherin 1, type 1, E-cadherin (epithelial)
  • naked mole-rat(101719565) cadherin 1, type 1, E-cadherin (epithelial)
  • Zebrafish(114424) cadherin 1, epithelial
  • cow(282637) cadherin 1, type 1, E-cadherin (epithelial)

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Mouse E-Cadherin ELISA Kit, for serum, plasma and cell culture supernatant,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Cadherin-pan antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Przeciwciało anty-E-kadherynowe, klon 2Q9Y7, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Monoclonal Anti-CD324-PE antibody produced in mouse, clone 67A4, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-E-Cadherin/CD324 Antibody, clone 19A11, ,
Reaktywność gatunkowa
canine, human
Zastosowanie
ELISA
immunocytochemistry

inhibition assay

western blot
Anti-E-Cadherin (CDH1) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM244, purified immunoglobulin,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Cell Lines

Numer produktu
Opis
Gatunek
MCF10A CELLS CDH1 (-/-), ,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
E-Cadherin human, recombinant, expressed in E. coli, 0.5 mg protein/mL,
Gatunek
human
E-Cadherin/Fc Chimera from mouse, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Gatunek
mouse

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CDH1,
Gatunek
human
MISSION® esiRNA, targeting mouse Cdh1,
Gatunek
mouse