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Merck

CDH4

cadherin 4, type 1, R-cadherin (retinal)

Synonimy:
CAD4, RCAD
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1002) Summary: This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
  • Mouse(12561) cadherin 4
  • Rat(114588) cadherin 4
  • naked mole-rat(101726465) cadherin 4, type 1, R-cadherin (retinal)
  • domestic guinea pig(100720758) cadherin 4, type 1, R-cadherin (retinal)
  • sheep(101122716) cadherin 4, type 1, R-cadherin (retinal)
  • chicken(419222) cadherin 4, type 1, R-cadherin (retinal)
  • cow(525796) cadherin 4, type 1, R-cadherin (retinal)
  • dog(100685099) cadherin 4, type 1, R-cadherin (retinal)
  • Zebrafish(30297) cadherin 4, retinal
  • domestic cat(101085708) cadherin 4, type 1, R-cadherin (retinal)

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human Cadherin-4 ELISA, for serum, plasma and cell culture supernatants,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti R Cadherin Antibody, clone 23GB5055, Rabbit Monoclonal, clone 23GB5055, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
western blot
Anti-CDH4 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, human, mouse, rat
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CDH4,
Gatunek
human
MISSION® esiRNA, targeting mouse Cdh4,
Gatunek
mouse