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Merck

CDK1

cyclin-dependent kinase 1

Synonimy:
CDC2, CDC28A, P34CDC2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(983) Summary: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
  • Mouse(12534) cyclin-dependent kinase 1
  • Rat(54237) cyclin-dependent kinase 1
  • dog(488997) cyclin-dependent kinase 1
  • Zebrafish(80973) cyclin-dependent kinase 1
  • chicken(396252) cyclin-dependent kinase 1
  • naked mole-rat(101717463) cyclin-dependent kinase 1
  • domestic guinea pig(100735946) cyclin-dependent kinase 1
  • Goat(100861361) cyclin-dependent kinase 1
  • cow(281061) cyclin-dependent kinase 1
  • sheep(100216432) cyclin-dependent kinase 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-CDK1/2/3(Thr14) Antibody, clone 23GB1430, Rabbit Monoclonal, clone 23GB1430, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
immunofluorescence

western blot
Anti-phospho-CDC2 (pThr161) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Przeciwciało anty-fosfo-Cdk1 (Thr14, Tyr15), klon CP3.2, clone CP3.2, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
western blot
Anty-fosfo-CDK1-Y15, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-Cdc2, fosfospecyficzne (Tyr15), Chemicon®, from rabbit,
Reaktywność gatunkowa
rat
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
R547, ≥98% (HPLC),
Gatunek
human
Flavopiridol hydrochloride hydrate, ≥98% (HPLC), powder,
Gatunek
human
Roscovitine, ≥98% (TLC),
Gatunek
human, mouse, rat

Proteins

Numer produktu
Opis
Gatunek
CDK1/CyclinB1, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
CDK1/Cyclin A2, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CDK1,
Gatunek
human