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Merck

CDK7

cyclin-dependent kinase 7

Synonimy:
CAK1, CDKN7, HCAK, MO15, STK1, p39MO15
Gatunek:
Human CDK7 (1022), Mouse Cdk7 (12572), Rat Cdk7 (171150), domestic guinea pig Cdk7 (100725955), naked mole-rat Cdk7 (101702664), sheep CDK7 (101119934), Horse CDK7 (100049964), Zebrafish cdk7 (405897), dog CDK7 (608441), domestic cat CDK7 (101086781) ...Więcej
Identyfikator UniProtKB:
P50613, Q9BS60, Q9UE19
Identyfikator genu:
  • Human(1022) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This protein forms a trimeric complex with cyclin H and MAT1, which functions as a Cdk-activating kinase (CAK). It is an essential component of the transcription factor TFIIH, that is involved in transcription initiation and DNA repair. This protein is thought to serve as a direct link between the regulation of transcription and the cell cycle. [provided by RefSeq, Jul 2008]
  • Mouse(12572) cyclin-dependent kinase 7
  • Rat(171150) cyclin-dependent kinase 7
  • domestic guinea pig(100725955) cyclin-dependent kinase 7
  • naked mole-rat(101702664) cyclin-dependent kinase 7
  • sheep(101119934) cyclin-dependent kinase 7
  • Horse(100049964) cyclin-dependent kinase 7
  • Zebrafish(405897) cyclin-dependent kinase 7
  • dog(608441) cyclin-dependent kinase 7
  • domestic cat(101086781) cyclin-dependent kinase 7
  • chicken(771294) cyclin-dependent kinase 7
  • cow(515462) cyclin-dependent kinase 7
  • fruit fly(31441) Cyclin-dependent kinase 7

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4504143
Anti-phospho-CDK7 (pThr170) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
ABE1317
Anti-phospho Cyclin-dependent kinase 7 (Thr170) Antibody, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ChIP
western blot
HPA007932
Anti-CDK7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
WH0001022M1
Monoclonal Anti-CDK7 antibody produced in mouse, clone 1G5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
C7089
Monoclonal Anti-Cdk7/CAK antibody produced in mouse, clone MO-1.1, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
F3055
Flavopiridol hydrochloride hydrate, ≥98% (HPLC), powder,
Gatunek
human
R7772
Roscovitine, ≥98% (TLC),
Gatunek
human, mouse, rat
O0886
Olomoucine, ≥98% (HPLC),
Gatunek
human, rat

Proteins

Numer produktu
Opis
Gatunek
14-476-M
Białko Cdk7/Cyklina H/MAT1 (kompleks CAK), aktywne, 10 µg, Active complex of recombinant full length human Cdk7, containing a C-terminal His6-tag, recombinant full-length human Cyclin H untagged & recombinant full-length human MAT1 containing an N-terminal GST-tag, for use in Kinase Assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EMU067531
MISSION® esiRNA, targeting mouse Cdk7,
Gatunek
mouse
EHU108561
MISSION® esiRNA, targeting human CDK7,
Gatunek
human

Small Molecule - Substrate

Numer produktu
Opis
Gatunek
12-526
Cdk7/9tide, ,
Gatunek
human