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Merck

CFP

complement factor properdin

Synonimy:
BFD, PFC, PFD, PROPERDIN
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5199) Summary: This gene encodes a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Feb 2009]
  • Mouse(18636) complement factor properdin
  • Rat(299314) complement factor properdin
  • Zebrafish(556399) complement factor properdin
  • domestic cat(101090086) complement factor properdin
  • dog(491859) complement factor properdin
  • Domestic Rabbit(100340696) complement factor properdin
  • sheep(101114678) complement factor properdin
  • cow(539605) complement factor properdin
  • Horse(100051317) complement factor properdin
  • naked mole-rat(101724230) complement factor properdin
  • domestic guinea pig(100728194) complement factor properdin

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-Perdin, klon 6E11A4, clone 6E11A4, from mouse,
Reaktywność gatunkowa
baboon, canine, human, rabbit
Zastosowanie
ELISA
immunohistochemistry

western blot
Przeciwciało anty-Perdin, klon 3A3E1, clone 3A3E1, from mouse,
Reaktywność gatunkowa
baboon, canine, human, rabbit
Zastosowanie
ELISA
immunohistochemistry

western blot
Przeciwciało anty-properdyna, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
human, mouse, nonhuman primates, rat
Zastosowanie
western blot
Anti-Properdin/CFP Antibody, clone 1K9 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Przeciwciało anty-Perdin, klon 6E9E6, clone 6E9E6, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CFP,
Gatunek
human