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Merck

CKMT1B

creatine kinase, mitochondrial 1B

Synonimy:
CKMT, CKMT1, UMTCK
Gatunek:
Human CKMT1B (1159), Rat Ckmt1b (29593), dog CKMT1B (478277), domestic cat CKMT1B (101097983), Horse CKMT1B (100056283), naked mole-rat Ckmt1b (101725224), sheep CKMT1B (101108520), cow CKMT1B (281692)
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1159) Summary: Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes, sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes. Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins. [provided by RefSeq, Jul 2008]
  • Rat(29593) creatine kinase, mitochondrial 1B
  • dog(478277) creatine kinase, mitochondrial 1B
  • domestic cat(101097983) creatine kinase, mitochondrial 1B
  • Horse(100056283) creatine kinase, mitochondrial 1B
  • naked mole-rat(101725224) creatine kinase, mitochondrial 1B
  • sheep(101108520) creatine kinase, mitochondrial 1B
  • cow(281692) creatine kinase, mitochondrial 1B

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB1400052
Monoclonal Anti-CKMT1B antibody produced in mouse, clone 2C8, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
SAB1403672
Monoclonal Anti-CKMT1B, (C-terminal) antibody produced in mouse, clone 2C9, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot