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Merck

CTSL

cathepsin L

Synonimy:
CATL, CTSL1, MEP
Gatunek:
Human CTSL (1514), Mouse Ctsl (13039)
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1514) Summary: The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]
  • Mouse(13039) cathepsin L

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ELISA

Numer produktu
Opis
Gatunek
RAB0635
Human CTSL / Cathepsin L1 ELISA Kit, ,
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB5702994
Przeciwciało przeciw katepsynie L/V/K/H, klon 2Q10F10, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
HPA070413
Anty-CTSL, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
SAB4300959
Anty-CTSL, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
C2970
Monoclonal Anti-Cathepsin L antibody produced in mouse, clone 33/2, ascites fluid,
Reaktywność gatunkowa
human, mink, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
microarray
western blot

Proteins

Numer produktu
Opis
Gatunek
219402
Cathepsin L, Human Liver, Cathepsin L, Human Liver, CAS 60616-82-2, is a native, the most potent of all the lysosomal proteinases. Plays a major role in the proteolysis of both cellular and endocytosed macromolecules.,
Gatunek
human
SRP0291
Cathepsin L Active human, recombinant, expressed in FreeStyle™ 293-F cells, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
EHU106791
MISSION® esiRNA, targeting human CTSL,
Gatunek
human