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Merck

CYP1B1

cytochrome P450, family 1, subfamily B, polypeptide 1

Synonimy:
CP1B, CYPIB1, GLC3A, P4501B1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1545) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. [provided by RefSeq, Jul 2008]
  • Mouse(13078) cytochrome P450, family 1, subfamily b, polypeptide 1
  • Rat(25426) cytochrome P450, family 1, subfamily b, polypeptide 1
  • dog(483038) cytochrome P450, family 1, subfamily B, polypeptide 1
  • chicken(421466) cytochrome P450, family 1, subfamily B, polypeptide 1
  • Zebrafish(100150054) cytochrome P450, family 1, subfamily B, polypeptide 1
  • chicken(428832) cytochrome P450, family 1, subfamily B, polypeptide 1
  • cow(511470) cytochrome P450, family 1, subfamily B, polypeptide 1

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało przeciwko cytochromowi P450 1B1, serum, Chemicon®,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-CYP1B1, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, human, mouse, rabbit, rat
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Rutaecarpine, >98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Cytochrome P450 human, 1B1 Isozyme Microsomes, with P450 Reductase, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human CYP1B1,
Gatunek
human