CYP2C19
cytochrome P450, family 2, subfamily C, polypeptide 19
Synonimy:
CPCJ, CYP2C, P450C2C, P450IIC19
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1557) Summary: This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
- sheep(100534653) cytochrome P450 2C19
- cow(510380) cytochrome P450, family 2, subfamily C, polypeptide 19
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Antibodies
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Zastosowanie
Anti-CYP2C19 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Small Molecule - Inhibitor
Proteins
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esiRNA
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