DAG1
dystroglycan 1 (dystrophin-associated glycoprotein 1)
Synonimy:
156DAG, A3a, AGRNR, DAG, MDDGC7, MDDGC9
Gatunek:
Human DAG1 (1605), Mouse Dag1 (13138), Rat Dag1 (114489), domestic cat DAG1 (100174781), sheep DAG1 (101103515), Horse DAG1 (100053150), Domestic Rabbit DAG1 (100009278), domestic guinea pig Dag1 (100734382), cow DAG1 (281439), naked mole-rat Dag1 (101714190) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(1605) Summary: Dystroglycan is a laminin binding component of the dystrophin-glycoprotein complex which provides a linkage between the subsarcolemmal cytoskeleton and the extracellular matrix. Dystroglycan 1 is a candidate gene for the site of the mutation in autosomal recessive muscular dystrophies. The dramatic reduction of dystroglycan 1 in Duchenne muscular dystrophy leads to a loss of linkage between the sarcolemma and extracellular matrix, rendering muscle fibers more susceptible to necrosis. Dystroglycan also functions as dual receptor for agrin and laminin-2 in the Schwann cell membrane. The muscle and nonmuscle isoforms of dystroglycan differ by carbohydrate moieties but not protein sequence. Alternative splicing results in multiple transcript variants all encoding the same protein.[provided by RefSeq, Apr 2010]
- Mouse(13138) dystroglycan 1
- Rat(114489) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- domestic cat(100174781) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- sheep(101103515) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Horse(100053150) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Domestic Rabbit(100009278) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- domestic guinea pig(100734382) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- cow(281439) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- naked mole-rat(101714190) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- chicken(100049058) dystroglycan 1 (dystrophin-associated glycoprotein 1)
- Zebrafish(286829) dystroglycan 1
- Thale Cress(825358) Dof zinc finger protein DOF3.7
- dog(476623) dystroglycan 1 (dystrophin-associated glycoprotein 1)
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-DAG1 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, guinea pig, horse, human, mouse, pig, rabbit, zebrafish
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-TROP2 Antibody, clone TrMab-29, ,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunohistochemistry
western blot
immunohistochemistry
western blot
Przeciwciało anty-α-Dystroglikan, klon VIA4-1, culture supernatant, clone VIA4-1, Upstate®,
Reaktywność gatunkowa
canine, guinea pig, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-α-Dystroglycan Antibody, clone VIA4-1 ZooMAb® Mouse Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
canine, guinea pig, human, mouse, rabbit, rat
Zastosowanie
immunocytochemistry
immunohistochemistry
western blot
immunohistochemistry
western blot
Anty-DAG1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence