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DNMT3A

DNA (cytosine-5-)-methyltransferase 3 alpha

Synonimy:
DNMT3A2, M.HsaIIIA
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1788) Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(13435) DNA methyltransferase 3A
  • Rat(444984) DNA (cytosine-5-)-methyltransferase 3 alpha
  • sheep(100500776) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Domestic Rabbit(100344715) DNA (cytosine-5-)-methyltransferase 3 alpha
  • cow(359716) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic cat(100510798) DNA (cytosine-5-)-methyltransferase 3 alpha
  • Horse(100055881) DNA (cytosine-5-)-methyltransferase 3 alpha
  • dog(482996) DNA (cytosine-5-)-methyltransferase 3 alpha
  • naked mole-rat(101718745) DNA (cytosine-5-)-methyltransferase 3 alpha
  • domestic guinea pig(100721625) DNA (cytosine-5-)-methyltransferase 3 alpha
  • chicken(421991) DNA (cytosine-5-)-methyltransferase 3 alpha

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti DNA methyltransferase 3 alpha Antibody, clone 23GB2230, Rabbit Monoclonal, clone 23GB2230, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
western blot
Anti-DNMT3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
Przeciwciało anty-DNMT3Aprodukowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
western blot
Anty-DNMT3A, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-DNMT3A2, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunocytochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
5-Azacytidine, Hybri-Max, γ-irradiated, lyophilized powder, BioXtra, suitable for hybridoma,
Gatunek
human
5-Aza-2′-deoxycytidine, ≥97%,
Gatunek
human
Azacitidine, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Azacytydyna, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
5-Azacytidine, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
DNMT3a Active human, recombinant, expressed in baculovirus infected insect cells,
Gatunek
human
DNMT3A/DNMT3L active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human DNMT3A,
Gatunek
human
MISSION® esiRNA, targeting mouse Dnmt3a,
Gatunek
mouse