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Merck

EIF2S1

eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Synonimy:
EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(1965) Summary: The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987 [PubMed 2948954]
  • Mouse(13665) eukaryotic translation initiation factor 2, subunit 1 alpha
  • Rat(54318) eukaryotic translation initiation factor 2, subunit 1 alpha
  • chicken(423279) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • Goat(100861133) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • domestic cat(101091455) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • sheep(101113414) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • domestic guinea pig(100716377) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • cow(327694) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • dog(480361) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
  • naked mole-rat(101723170) eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-eIF-2α Antibody, clone 3M6 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
flow cytometry

immunocytochemistry

western blot
Monoclonal Anti-EIF2S1 (phospho S51) antibody produced in rabbit, clone IO-5,
Reaktywność gatunkowa
human
Zastosowanie
flow cytometry
immunofluorescence

immunohistochemistry

western blot
Anti-phospho-EIF2S1 (pSer51) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anty-fosfo-eIF2α-S51, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anty-EIF2S1, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human EIF2S1,
Gatunek
human
MISSION® esiRNA, targeting mouse Eif2s1,
Gatunek
mouse