F8
coagulation factor VIII, procoagulant component
Synonimy:
AHF, DXS1253E, F8B, F8C, FVIII, HEMA
Gatunek:
Human F8 (2157), Mouse F8 (14069), Rat F8 (302470), naked mole-rat F8 (101725450), domestic guinea pig F8 (100720831), Zebrafish f8 (100302404), chicken F8 (422199), dog F8 (403875), domestic cat F8 (101092751), cow F8 (100271720) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2157) Summary: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
- Mouse(14069) coagulation factor VIII
- Rat(302470) coagulation factor VIII, procoagulant component
- naked mole-rat(101725450) coagulation factor VIII, procoagulant component
- domestic guinea pig(100720831) coagulation factor VIII, procoagulant component
- Zebrafish(100302404) coagulation factor VIII, procoagulant component
- chicken(422199) coagulation factor VIII, procoagulant component
- dog(403875) coagulation factor VIII, procoagulant component
- domestic cat(101092751) coagulation factor VIII, procoagulant component
- cow(100271720) coagulation factor VIII, procoagulant component
- sheep(100359363) coagulation factor VIII, procoagulant component
- Domestic Rabbit(100303761) coagulation factor VIII, procoagulant component
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Factor VIII antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
western blot
western blot
Monoclonal Anti-F8 antibody produced in mouse, clone 5E9B2, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Przeciwciało anty-VWF (czynnik von Willebranda), klon GMA-022, clone GMA-022, Upstate®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało przeciwko czynnikowi VIII, klon GMA-012, clone GMA-012, Upstate®, from mouse,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Anti-von Willebrand Factor Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
immunohistochemistry
esiRNA
Numer produktu
Opis
Gatunek