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Merck

FLNA

filamin A, alpha

Synonimy:
ABP-280, ABPX, CSBS, CVD1, FLN, FLN-A, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2316) Summary: The protein encoded by this gene is an actin-binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. The encoded protein is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. This protein interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in this gene are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4), otopalatodigital syndromes (OPD1, OPD2), frontometaphyseal dysplasia (FMD), Melnick-Needles syndrome (MNS), and X-linked congenital idiopathic intestinal pseudoobstruction (CIIPX). Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2009]
  • Mouse(192176) filamin, alpha
  • Rat(293860) filamin A, alpha
  • domestic guinea pig(100725162) filamin A, alpha
  • Zebrafish(562529) filamin A, alpha (actin binding protein 280)
  • chicken(395261) filamin A, alpha
  • naked mole-rat(101702004) filamin A, alpha
  • Zebrafish(100534866) filamin A, alpha
  • sheep(101120390) filamin A, alpha
  • dog(481084) filamin A, alpha
  • Domestic Rabbit(100328754) filamin A, alpha
  • cow(281165) filamin A, alpha
  • domestic cat(101082637) filamin A, alpha

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Filamin A antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Anti-Filamin antibody,Mouse monoclonal, clone PM6/317, purified from hybridoma cell culture,
Reaktywność gatunkowa
bovine, canine, hamster, human, monkey
Zastosowanie
immunofluorescence
western blot
Anti-FLNA antibody produced in rabbit, Ab2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anti-FLNA antibody produced in rabbit, Ab3, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Przeciwciało anty-fosfo-FLNA-S2152wytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human FLNA,
Gatunek
human