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FLT1

fms-related tyrosine kinase 1

Synonimy:
FLT, FLT-1, VEGFR-1, VEGFR1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2321) Summary: This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.[provided by RefSeq, May 2009]
  • Mouse(14254) FMS-like tyrosine kinase 1
  • Rat(54251) FMS-related tyrosine kinase 1
  • domestic guinea pig(100732326) fms-related tyrosine kinase 1
  • Zebrafish(544667) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • dog(403727) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • domestic cat(101088292) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • sheep(443088) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • chicken(374100) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Horse(100061940) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • cow(503620) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Domestic Rabbit(100343352) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • Horse(100033957) fms-related tyrosine kinase 1 (vascular endothelial growth factor/vascular permeability factor receptor)
  • naked mole-rat(101711333) fms-related tyrosine kinase 1

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human VEGFR1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Gatunek
human
Rat VEGFR1 ELISA, for serum, plasma and cell culture supernatants,
Gatunek
rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-VEGFR1 (pTyr1333) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse, clone FLT-11, ascites fluid,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)

western blot
Monoclonal Anti-Vascular Endothelial Growth Factor Receptor-1 antibody produced in mouse, clone FLT-19, tissue culture supernatant,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry

immunoprecipitation (IP)

microarray
Monoclonal Anti-FLT1 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0344, purified immunoglobulin, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Monoklonalny anty-FLT1, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0345, purified immunoglobulin, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
SU 4312, ≥98% (HPLC),
Gatunek
human
SU 5416, ≥98% (HPLC),
Gatunek
human, mouse
Pazopanib, ,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Flt1 active human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE),
Gatunek
human
VEGF Receptor-1 (Flt-1)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human FLT1,
Gatunek
human