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Merck

GABBR2

gamma-aminobutyric acid (GABA) B receptor, 2

Synonimy:
GABABR2, GPR51, GPRC3B, HG20, HRIHFB2099
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(9568) Summary: The multi-pass membrane protein encoded by this gene belongs to the G-protein coupled receptor 3 family and GABA-B receptor subfamily. The GABA-B receptors inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters, and the activity of ion channels and adenylyl cyclase. This receptor subunit forms an active heterodimeric complex with GABA-B receptor subunit 1, neither of which is effective on its own. Allelic variants of this gene have been associated with nicotine dependence.[provided by RefSeq, Jan 2010]
  • Mouse(242425) gamma-aminobutyric acid (GABA) B receptor, 2
  • Rat(83633) gamma-aminobutyric acid (GABA) B receptor 2
  • domestic guinea pig(100170764) gamma-aminobutyric acid (GABA) B receptor, 2
  • naked mole-rat(101719923) gamma-aminobutyric acid (GABA) B receptor, 2
  • Horse(100063963) gamma-aminobutyric acid (GABA) B receptor, 2
  • sheep(101103544) gamma-aminobutyric acid (GABA) B receptor, 2
  • Domestic Rabbit(100346845) gamma-aminobutyric acid (GABA) B receptor, 2
  • domestic cat(101093058) gamma-aminobutyric acid (GABA) B receptor, 2
  • cow(517040) gamma-aminobutyric acid (GABA) B receptor, 2
  • dog(481627) gamma-aminobutyric acid (GABA) B receptor, 2
  • Zebrafish(560267) gamma-aminobutyric acid (GABA) B receptor, 2
  • chicken(420979) gamma-aminobutyric acid (GABA) B receptor, 2

Custom & Knockdown Gene Products

Small Molecule - Agonist

Numer produktu
Opis
Gatunek
Baclofen, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Baclofen, Pharmaceutical Secondary Standard; Certified Reference Material,
Gatunek
human
Baclofen, British Pharmacopoeia (BP) Reference Standard,
Gatunek
human
Baklofen, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
(±)-Baclofen, ≥98% (HPLC), solid,
Gatunek
human, rat

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
CGP-13501, ≥98% (HPLC), solid,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
2-Hydroxysaclofen, ≥98% (TLC), solid,
Gatunek
human
Phaclofen, solid,
Gatunek
human
(±)-Baclofen, ≥98% (HPLC), solid,
Gatunek
human, rat
Saclofen, solid,
Gatunek
mouse, human, rat
γ-Aminobutyric acid, ≥99%,
Gatunek
human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GABBR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-GABAB Receptor 2 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Reaktywność gatunkowa
rat
Zastosowanie
western blot
Anti GABBR2 Antibody, clone 23GB5500, Rabbit Monoclonal, clone 23GB5500, recombinant rabbit monoclonal, expressed in HEK293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
western blot
Anti-GABBR2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Monoklonalny anty-Gaba-Breceptor 2 - Rpe, clone S81-2, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
NO-711 hydrochloride, ≥98% (HPLC),
Gatunek
human
(±)-Vigabatrin, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human GABBR2,
Gatunek
human