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Merck

GCLM

glutamate-cysteine ligase, modifier subunit

Synonimy:
GLCLR
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2730) Summary: Glutamate-cysteine ligase, also known as gamma-glutamylcysteine synthetase, is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits, a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq, Jul 2008]
  • Mouse(14630) glutamate-cysteine ligase, modifier subunit
  • Rat(29739) glutamate cysteine ligase, modifier subunit
  • dog(612283) glutamate-cysteine ligase, modifier subunit
  • domestic guinea pig(100725164) glutamate-cysteine ligase, modifier subunit
  • domestic cat(101081562) glutamate-cysteine ligase, modifier subunit
  • fruit fly(248194) Glutamate-cysteine ligase modifier subunit
  • chicken(424492) glutamate-cysteine ligase, modifier subunit
  • naked mole-rat(101703324) glutamate-cysteine ligase, modifier subunit
  • sheep(101117899) glutamate-cysteine ligase, modifier subunit
  • Zebrafish(333974) glutamate-cysteine ligase, modifier subunit
  • cow(525659) glutamate-cysteine ligase, modifier subunit

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-GCLM antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało anty-GCLMwytwarzane u królika, ,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
Anty-GCLM, ,
Reaktywność gatunkowa
Zastosowanie
western blot
Anti-GCLM antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-GCLM antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
L-Buthionine-sulfoximine, ≥97% (TLC),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human GCLM,
Gatunek
human
MISSION® esiRNA, targeting mouse Gclm,
Gatunek
mouse