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Merck

GRIN2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

Synonimy:
GluN2B, MRD6, NMDAR2B, NR2B, hNR3
Gatunek:
Human GRIN2B (2904), Mouse Grin2b (14812), Rat Grin2b (24410), cow GRIN2B (537804), dog GRIN2B (494009), chicken GRIN2B (417965), naked mole-rat Grin2b (101723091), domestic guinea pig Grin2b (100731840), Horse GRIN2B (100063746), domestic cat GRIN2B (101094356)
Identyfikator UniProtKB:
Q13224, Q12919, Q13220, Q13225, Q14CU4, Q9UM56
Identyfikator genu:
  • Human(2904) Summary: N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of three different subunits: NR1 (GRIN1), NR2 (GRIN2A, GRIN2B, GRIN2C, or GRIN2D) and NR3 (GRIN3A or GRIN3B). The NR2 subunit acts as the agonist binding site for glutamate. This receptor is the predominant excitatory neurotransmitter receptor in the mammalian brain. [provided by RefSeq, Jul 2008]
  • Mouse(14812) glutamate receptor, ionotropic, NMDA2B (epsilon 2)
  • Rat(24410) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • cow(537804) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • dog(494009) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • chicken(417965) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • naked mole-rat(101723091) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic guinea pig(100731840) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • Horse(100063746) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • domestic cat(101094356) glutamate receptor, ionotropic, N-methyl D-aspartate 2B
  • sheep(101118179) glutamate receptor, ionotropic, N-methyl D-aspartate 2B

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Small Molecule - Agonist

Numer produktu
Opis
Gatunek
R1401
Reversin 205, ≥98% (HPLC), film,
Gatunek
mouse, rat, human
C3909
D-Cycloserine, synthetic,
Gatunek
human
D2531
Dextromethorphan hydrobromide monohydrate, ≥99% (TLC),
Gatunek
human
M3262
N-Methyl-D-aspartic acid, ≥98% (TLC), solid,
Gatunek
human, rat
A0326
(S)-AMPA, ≥97%,
Gatunek
mouse, human, rat

Small Molecule - Allosteric Modulator

Numer produktu
Opis
Gatunek
K1884
S-(+)-Ketamine hydrochloride, ,
Gatunek
human
Y0000450
Ketamine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
K2753
(±)-Ketamine hydrochloride, solid,
Gatunek
human
K-002
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Gatunek
human
A6981
Acamprosate calcium, ≥98% (HPLC), powder,
Gatunek
human

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
R7150
Ro 25-6981 hydrochloride hydrate, ≥98% (HPLC), powder,
Gatunek
human
299650
2-Phenylquinoline, 99%,
Gatunek
rat
R8900
Ro 8-4304, solid,
Gatunek
human
A0637
DL-2-Aminoadipic acid, ≥99%,
Gatunek
rat
E2031
Eliprodil, ≥98% (HPLC), powder,
Gatunek
human, rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
SAB4501306
Anti-NMDAR2B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
SAB4501305
Anti-NMDAR2B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
SAB2104208
Anti-GRIN2B antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
SAB4504677
Anti-phospho-NMDAR2B (pTyr1336) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
SAB5700562
Przeciwciało anty-fosfo-GRIN2B-Y1070produkowane u królika, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
D8816
N-(3,3-Diphenylpropyl)glycinamide, >98% (HPLC), solid,
Gatunek
human
A7127
Agmatine sulfate salt, ≥97%, powder,
Gatunek
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Gatunek
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
P0547
Pentamidine isethionate salt, powder,
Gatunek
human
75517
Orphenadrine hydrochloride, ≥98.0% (AT),
Gatunek
human
Y0001181
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
Y0000100
Orphenadrine hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human
G1251
L-Glutamic acid, ReagentPlus®, ≥99% (HPLC),
Gatunek
rat, human

esiRNA

Numer produktu
Opis
Gatunek
EHU036291
MISSION® esiRNA, targeting human GRIN2B,
Gatunek
human
EMU067251
MISSION® esiRNA, targeting mouse Grin2b,
Gatunek
mouse