GRN
granulin
Synonimy:
CLN11, GEP, GP88, PCDGF, PEPI, PGRN
Gatunek:
Human GRN (2896), Mouse Grn (14824), Rat Grn (29143), fruit fly grn (40962), dog GRN (480501), Horse GRN (100051035), domestic cat GRN (101100680), cow GRN (767942), sheep GRN (101115470), Domestic Rabbit GRN (100349528) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(2896) Summary: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis. [provided by RefSeq, Jul 2008]
- Mouse(14824) granulin
- Rat(29143) granulin
- fruit fly(40962) grain
- dog(480501) granulin
- Horse(100051035) granulin
- domestic cat(101100680) granulin
- cow(767942) granulin
- sheep(101115470) granulin
- Domestic Rabbit(100349528) granulin
- domestic guinea pig(100135533) granulin
- naked mole-rat(101715753) granulin
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ELISA
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-GRN antibody produced in mouse, clone 1F5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-GRN antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-GRN antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Przeciwciało przeciw granulinie, klon 8O5Q5, królicze monoklonalne, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Proteins
esiRNA
Numer produktu
Opis
Gatunek