IL12B
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
Synonimy:
CLMF, CLMF2, IL-12B, NKSF, NKSF2
Gatunek:
Human IL12B (3593), Mouse Il12b (16160), Rat Il12b (64546), cow IL12B (281857), chicken IL12B (404671), Horse IL12B (100034222), sheep IL12B (443472), naked mole-rat Il12b (101701309), domestic cat IL12B (768273), dog IL12B (403976)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(3593) Summary: This gene encodes a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. [provided by RefSeq, Jul 2008]
- Mouse(16160) interleukin 12b
- Rat(64546) interleukin 12B
- cow(281857) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- chicken(404671) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- Horse(100034222) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- sheep(443472) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- naked mole-rat(101701309) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- domestic cat(768273) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- dog(403976) interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
- domestic guinea pig(100135554) interleukin 12b
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Numer produktu
Opis
Gatunek
Human IL-12 p40 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-IL-12 p40 Antibody, clone C15.6, ,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
flow cytometry
immunohistochemistry
neutralization
radioimmunoassay
western blot
flow cytometry
immunohistochemistry
neutralization
radioimmunoassay
western blot
Anti-IL-12B Antibody, clone 1N3 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
affinity binding assay
western blot
affinity binding assay
western blot
Przeciwciało anty-IL-12/IL-23 p40 (mysz), PE, klon C17.8, clone C17.8, from rat, PE,
Reaktywność gatunkowa
mouse
Zastosowanie
flow cytometry
Przeciwciało anty-IL-12/IL-23 p40 (mysz), PE, klon C17.8, clone C17.8, from rat, PE,
Reaktywność gatunkowa
mouse
Zastosowanie
flow cytometry
Proteins
Numer produktu
Opis
Gatunek
Interleukin-12 human, ≥97% (SDS-PAGE and N-terminal analysis), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Gatunek
human
Interleukin-12 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Gatunek
mouse