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IL6ST

interleukin 6 signal transducer (gp130, oncostatin M receptor)

Synonimy:
CD130, CDW130, GP130, IL-6RB
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3572) Summary: The protein encoded by this gene is a signal transducer shared by many cytokines, including interleukin 6 (IL6), ciliary neurotrophic factor (CNTF), leukemia inhibitory factor (LIF), and oncostatin M (OSM). This protein functions as a part of the cytokine receptor complex. The activation of this protein is dependent upon the binding of cytokines to their receptors. vIL6, a protein related to IL6 and encoded by the Kaposi sarcoma-associated herpesvirus, can bypass the interleukin 6 receptor (IL6R) and directly activate this protein. Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A related pseudogene has been identified on chromosome 17. [provided by RefSeq, Jul 2010]
  • Mouse(16195) interleukin 6 signal transducer
  • Rat(25205) interleukin 6 signal transducer
  • Domestic Rabbit(100349330) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • sheep(101113174) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • cow(522155) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • Horse(100051700) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • domestic cat(101089832) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • dog(403545) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • chicken(395684) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • naked mole-rat(101703833) interleukin 6 signal transducer (gp130, oncostatin M receptor)
  • Zebrafish(100006778) interleukin 6 signal transducer

Custom & Knockdown Gene Products

ELISA

Numer produktu
Opis
Gatunek
Human sgp130 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human
Mouse Il6st / Interleukin-6 Receptor Subunit Beta ELISA Kit, for serum, plasma and cell culture supernatants,
Gatunek
mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-CD130 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunofluorescence

immunohistochemistry

western blot
Anti-IL6ST antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty IL6ST, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-CD130/IL-6RB Antibody, clone 2I13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
canine, horse, human, monkey, porcine, rat
Zastosowanie
affinity binding assay
immunocytochemistry

western blot
Anti-IL6ST antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, canine, guinea pig, horse, human, rabbit, rat
Zastosowanie
immunohistochemistry
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human IL6ST,
Gatunek
human
MISSION® esiRNA, targeting mouse Il6st,
Gatunek
mouse