Przejdź do zawartości
Merck

ITGAV

integrin, alpha V

Synonimy:
CD51, MSK8, VNRA, VTNR
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3685) Summary: This gene encodes a protein that is a member of the integrin superfamily. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein undergoes post-translational cleavage to yield disulfide-linked heavy and light chains that combine with multiple integrin beta chains to form different integrins. This protein has been shown to heterodimerize with beta 1, beta 3, beta 5, beta 6, and beta 8; the heterodimer of alpha v and beta 3 is the Vitronectin receptor. This protein interacts with several extracellular matrix proteins to mediate cell adhesion and may play a role in cell migration. It is proposed that this protein may regulate angiogenesis and cancer progression. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, May 2013]
  • Mouse(16410) integrin alpha V
  • Rat(296456) integrin, alpha V
  • dog(488437) integrin, alpha V
  • naked mole-rat(101717672) integrin, alpha V
  • domestic guinea pig(100728575) integrin, alpha V
  • domestic cat(101085820) integrin, alpha V
  • chicken(396420) integrin, alpha V
  • Zebrafish(100151255) integrin, alpha V
  • Domestic Rabbit(100008956) integrin, alpha V
  • cow(281875) integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51)
  • sheep(443143) integrin, alpha V
  • Horse(100068706) integrin, alpha V

Custom & Knockdown Gene Products

Small Molecule - Antagonist

Numer produktu
Opis
Gatunek
Gly-Arg-Gly-Asp-Ser-Pro-Lys, ≥97% (HPLC),
Gatunek
human

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Integrin αVβ6 Antibody, clone 10D5, azide free, clone 10D5, Chemicon®, from mouse,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
flow cytometry
immunoprecipitation (IP)
Anti-Integrin αVβ5 Antibody, clone P1F6, clone P1F6, Chemicon®, from mouse,
Reaktywność gatunkowa
chicken, human
Zastosowanie
flow cytometry
immunocytochemistry

immunohistochemistry

immunoprecipitation (IP)
Przeciwciało anty-Integryna αVβ5, klon P1F6, koniugat fikoerytryny, clone P1F6, from mouse, PE,
Reaktywność gatunkowa
chicken, hamster, human
Zastosowanie
flow cytometry
Anti-Integrin αVβ3 Antibody, clone LM609, Phycoerythrin conjugated, clone LM609, Chemicon®, from mouse,
Reaktywność gatunkowa
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Zastosowanie
flow cytometry
immunohistochemistry
Anti-Integrin αVβ3 Antibody, clone LM609, clone LM609, Chemicon®, from mouse,
Reaktywność gatunkowa
avian, bovine, canine, chicken, human, monkey, pig, rabbit
Zastosowanie
flow cytometry
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ITGAV,
Gatunek
human
MISSION® esiRNA, targeting mouse Itgav,
Gatunek
mouse