LCK
lymphocyte-specific protein tyrosine kinase
Synonimy:
LSK, YT16, p56lck, pp58lck
Gatunek:
Human LCK (3932), Mouse Lck (16818), Rat Lck (313050), chicken LCK (396460), Zebrafish lck (414333), domestic cat LCK (101098805), dog LCK (478151), Domestic Rabbit LCK (100349102), sheep LCK (100216439), cow LCK (508890) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(3932) Summary: This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq, Jul 2008]
- Mouse(16818) lymphocyte protein tyrosine kinase
- Rat(313050) lymphocyte-specific protein tyrosine kinase
- chicken(396460) lymphocyte-specific protein tyrosine kinase
- Zebrafish(414333) lymphocyte-specific protein tyrosine kinase
- domestic cat(101098805) lymphocyte-specific protein tyrosine kinase
- dog(478151) lymphocyte-specific protein tyrosine kinase
- Domestic Rabbit(100349102) lymphocyte-specific protein tyrosine kinase
- sheep(100216439) lymphocyte-specific protein tyrosine kinase
- cow(508890) lymphocyte-specific protein tyrosine kinase
- Horse(100146139) lymphocyte-specific protein tyrosine kinase
- naked mole-rat(101714396) lymphocyte-specific protein tyrosine kinase
- domestic guinea pig(100728811) lymphocyte-specific protein tyrosine kinase
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ELISA
Numer produktu
Opis
Gatunek
Small Molecule - Antagonist
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-LCK antibody produced in mouse, clone 3F7-F5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Lck Antibody, clone 2B20 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
Anty-fosfo-Lck-Y505, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-LCK antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
bovine, canine, human, mouse, pig, rat
Zastosowanie
ELISA
western blot
western blot
ANTI-LCK antibody produced in mouse, clone 8B10, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
western blot
Small Molecule - Inhibitor
Numer produktu
Opis
Gatunek
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Gatunek
human