LDLR
low density lipoprotein receptor
Synonimy:
FH, FHC, LDLCQ2
Gatunek:
Human LDLR (3949), Mouse Ldlr (16835), Rat Ldlr (300438), dog LDLR (100683160), cow LDLR (281276), Zebrafish ldlr (387529), domestic cat LDLR (101080362), naked mole-rat Ldlr (101703463), Domestic Rabbit LDLR (100009086), chicken LDLR (395103)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(3949) Summary: The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Sep 2010]
- Mouse(16835) low density lipoprotein receptor
- Rat(300438) low density lipoprotein receptor
- dog(100683160) low density lipoprotein receptor
- cow(281276) low density lipoprotein receptor
- Zebrafish(387529) low density lipoprotein receptor
- domestic cat(101080362) low density lipoprotein receptor
- naked mole-rat(101703463) low density lipoprotein receptor
- Domestic Rabbit(100009086) low density lipoprotein receptor
- chicken(395103) low density lipoprotein receptor
- domestic guinea pig(100724238) low density lipoprotein receptor
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ELISA
Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-LDLR antibody produced in rabbit, Ab1, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-LDL-R antibody produced in chicken, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-Low Density Lipoprotein Antibody, copper oxidized, serum, Chemicon®,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-LDL Receptor Antibody, clone 2N19, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, rat
Zastosowanie
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-LDLR Antibody, clone C7, clone C7, from mouse,
Reaktywność gatunkowa
bovine, human
Zastosowanie
western blot