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Merck

LILRB3

leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3

Synonimy:
CD85A, HL9, ILT-5, ILT5, LILRA6, LIR-3, LIR3, PIRB
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(11025) Summary: This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(65146) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • Horse(100054321) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • cow(790139) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • cow(507024) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • domestic cat(101082610) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • cow(100139766) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • domestic guinea pig(100728502) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
  • naked mole-rat(101722653) leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-Lilrb3 wytwarzane u królików, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human LILRB3,
Gatunek
human
MISSION® esiRNA, targeting mouse Lilrb3,
Gatunek
mouse