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Merck

MAP2K7

mitogen-activated protein kinase kinase 7

Synonimy:
Jnkk2, MAPKK7, MKK7, PRKMK7, SAPKK-4, SAPKK4
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5609) Summary: The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2,MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found, but only one transcript variant has been supported and defined. [provided by RefSeq, Jul 2008]
  • Mouse(26400) mitogen-activated protein kinase kinase 7
  • Rat(363855) mitogen activated protein kinase kinase 7
  • dog(485004) mitogen-activated protein kinase kinase 7
  • Zebrafish(560913) mitogen-activated protein kinase kinase 7
  • domestic guinea pig(100731057) mitogen-activated protein kinase kinase 7
  • domestic cat(101095157) mitogen-activated protein kinase kinase 7
  • sheep(100302082) mitogen-activated protein kinase kinase 7
  • cow(787278) mitogen-activated protein kinase kinase 7
  • naked mole-rat(101710666) mitogen-activated protein kinase kinase 7

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MAP2K7 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anty-fosfo-MAP2K7(pSer271), affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-MKK7/SKK4, klon 3F6.5, clone 3F6.5, from mouse,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunocytochemistry
western blot
Przeciwciało anty-fosfo-MKK7/SKK4 (Thr275/Ser277), Upstate®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Anty-MAP2K7, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
PD 98,059, solid,
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Białko MKK7β1, aktywne, 10 µg, Active, N-terminal GST-tagged, recombinant, human MKK7β1, amino acids 2-end. For use in Kinase Assays.,
Gatunek
human
Białko MKK7β1, nieaktywne, 50 g, Unactive, N-terminal GST-tagged, recombinant, human MKK7β1 amino acids 2-end, for use in Kinase Assays.,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Map2k7,
Gatunek
mouse
MISSION® esiRNA, targeting human MAP2K7,
Gatunek
human