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MAPK7

mitogen-activated protein kinase 7

Synonimy:
BMK1, ERK4, ERK5, PRKM7
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(5598) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is specifically activated by mitogen-activated protein kinase kinase 5 (MAP2K5/MEK5). It is involved in the downstream signaling processes of various receptor molecules including receptor type kinases, and G protein-coupled receptors. In response to extracelluar signals, this kinase translocates to cell nucleus, where it regulates gene expression by phosphorylating, and activating different transcription factors. Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  • Mouse(23939) mitogen-activated protein kinase 7
  • Rat(114509) mitogen-activated protein kinase 7
  • Zebrafish(541323) mitogen-activated protein kinase 7
  • domestic cat(101097357) mitogen-activated protein kinase 7
  • cow(537703) mitogen-activated protein kinase 7
  • dog(489532) mitogen-activated protein kinase 7
  • Domestic Rabbit(100338535) mitogen-activated protein kinase 7
  • sheep(101110073) mitogen-activated protein kinase 7
  • naked mole-rat(101726391) mitogen-activated protein kinase 7
  • domestic guinea pig(100728396) mitogen-activated protein kinase 7

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-ERK5 (pThr218/pTyr220) antibody produced in rabbit, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
Anty-MAPK7, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Przeciwciało anty-ERK5, klon 5C1P5, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunohistochemistry
western blot
Anty-MAPK7, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anti-ERK5 Antibody, clone 2H15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
bovine, canine, feline, human, monkey, mouse, porcine
Zastosowanie
ELISA
affinity binding assay

immunofluorescence

immunohistochemistry

western blot

Proteins

Numer produktu
Opis
Gatunek
ERK5, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MAPK7,
Gatunek
human
MISSION® esiRNA, targeting mouse Mapk7,
Gatunek
mouse