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MAPKAPK5

mitogen-activated protein kinase-activated protein kinase 5

Synonimy:
MAPKAP-K5, MK-5, MK5, PRAK
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(8550) Summary: The protein encoded by this gene is a tumor suppressor and member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. The encoded protein is found in the nucleus but translocates to the cytoplasm upon phosphorylation and activation. This kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Nov 2012]
  • Mouse(17165) MAP kinase-activated protein kinase 5
  • Rat(498183) mitogen-activated protein kinase-activated protein kinase 5
  • naked mole-rat(101703557) mitogen-activated protein kinase-activated protein kinase 5
  • cow(535625) mitogen-activated protein kinase-activated protein kinase 5
  • Zebrafish(436608) mitogen-activated protein kinase-activated protein kinase 5
  • dog(477480) mitogen-activated protein kinase-activated protein kinase 5
  • domestic guinea pig(100730794) mitogen-activated protein kinase-activated protein kinase 5
  • sheep(101116258) mitogen-activated protein kinase-activated protein kinase 5
  • domestic cat(101082699) mitogen-activated protein kinase-activated protein kinase 5
  • chicken(373929) mitogen-activated protein kinase-activated protein kinase 5
  • Horse(100057579) mitogen-activated protein kinase-activated protein kinase 5

Custom & Knockdown Gene Products

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Monoclonal Anti-MAPKAPK5, (C-terminal) antibody produced in mouse, clone 3D7, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
immunofluorescence

western blot
Monoclonal Anti-MAPKAPK5 antibody produced in mouse, clone 2D5, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
ANTI-PRAK (MAPKAPK5) (T182) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-MAPKAPK5 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry

Proteins

Numer produktu
Opis
Gatunek
Białko PRAK, nieaktywne, ,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MAPKAPK5,
Gatunek
human
MISSION® esiRNA, targeting human MAPKAPK5 (2),
Gatunek
human